# Guanfacine Withdrawal: All You Need to Know

Written by [Olga Molina, D.S.W., LCSW](https://www.talkspace.com/mental-health/conditions/author/olgamolina/)  
Published Jun 28, 2023  
Clinically reviewed by [Reshawna Chapple, PhD, LCSW](https://www.talkspace.com/mental-health/conditions/author/reshawna-chapple/)  
Updated Oct 22, 2024

Guanfacine withdrawal is a serious concern for anyone taking this non-stimulant medication. Guanfacine, also known by the brand name Intuniv, is a prescription drug [used to treat](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344946/#:~:text=There%20is%20moderate%2Dquality%20evidence,and%20without%20ODD%20or%20CD.) attention-deficit hyperactivity disorder (ADHD) and ADHD with oppositional defiant disorder, along with some other conditions.

The ADHD medication works by calming the brain and helping with [focus and concentration](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494608/). Abrupt discontinuation of Guanfacine may result in various unwanted symptoms ranging from mild to severe. Understanding what to expect and how to avoid Guanfacine withdrawal means you can stop taking this medication efficiently and safely.

Learn about Guanfacine withdrawal symptoms and what kind of Guanfacine withdrawal timeline you should expect here.

## Can Guanfacine Be Stopped Cold Turkey?

It is not recommended that anyone stop taking Guanfacine suddenly without consulting their doctor or healthcare provider first. Abruptly discontinuing Guanfacine use can cause withdrawal symptoms such as anxiety, depression, irritability, insomnia, headaches, nausea, or vomiting, which may persist for weeks or months. After abruptly stopping the medication, these symptoms may last for an extended period.

> “Guanfacine should not be discontinued immediately. It is important to speak to your doctor about how to taper off the medication.”  
> – [Talkspace Therapist Dr. Olga Molina, D.S.W., LCSW](https://www.talkspace.com/therapists/profile/olga-molina-3253983)

## Withdrawal Symptoms of Guanfacine

When coming off any medication, it’s essential to understand the potential risks of abrupt withdrawal. For example, when discontinuing your Guanfacine treatment suddenly, there are several possible symptoms you might experience, such as:

- **Dizziness**: Can occur if you suddenly stop taking Guanfacine without a proper taper schedule.
- **Nausea/vomiting**: It’s common to feel queasy as you come off Guanfacine.
- **Headaches/migraines**: These are common occurrences reported by people who stop taking Guanfacine without slowly tapering off.
- **Irritability**: May include augmented uneasiness or restlessness.
- **Anxiety**: Some people feel anxious or nervous when they discontinue Guanfacine.

Abruptly stopping this medication can also lead to a sudden increase in blood pressure, which should be monitored carefully.

## How Long Does Guanfacine Withdrawal Last?

Guanfacine withdrawal can be a complex process with physical and psychological symptoms. The length of withdrawal symptoms can depend on the dose you've been taking and any other drugs in the body. Withdrawal from Guanfacine can range from a couple of days to many weeks, contingent upon your individual body chemistry and how long you’ve been taking the medication.

### Guanfacine withdrawal timeline

Withdrawal from Guanfacine typically ranges from 1 week to a month after ceasing usage. Within 24 hours of ceasing use, symptoms may start to manifest and can last up to 2 weeks before dissipating.

## How to Cope with a Guanfacine Withdrawal

To ensure optimal health and minimize withdrawal symptoms, it’s recommended to stay hydrated and eat nutritious meals. Avoid substances like alcohol during Guanfacine withdrawal. Additionally, regular exercise will help reduce stress levels, contributing significantly to overall mental health and well-being.

> “Withdrawal symptoms of Guanfacine can include headaches, tremors, agitation, and nervousness. To cope with withdrawal symptoms, contact your doctor and seek medical attention if necessary.”  
> – [Talkspace Therapist Dr. Olga Molina, D.S.W., LCSW](https://www.talkspace.com/therapists/profile/olga-molina-3253983)

## How Do I Safely Come Off Guanfacine?

To safely come off Guanfacine, it's best to gradually decrease use over a few weeks rather than abruptly stopping. Tapering off slowly allows your body more time to adjust without shock from sudden changes in dosage amounts. Your doctor will likely advise reducing doses by small increments until none are taken, minimizing withdrawal symptoms like lightheadedness and migraine.

In addition to tapering, implementing lifestyle changes like stress reduction techniques such as yoga, meditation, and exercise can help promote better mental and physical health overall.

## Talk with a Licensed Psychiatrist

If you aren’t liking the side effects of Guanfacine, consider talking to a psychiatrist. It’s crucial to find a doctor you feel comfortable discussing your thoughts and experiences with, to get the most out of your treatment plan.

If you or someone you know is experiencing Guanfacine withdrawal, consider seeking professional online mental health treatment to help manage the symptoms.